The rapid expansion of global trade and human activities has resulted in a massive increase in wastewater pollution into the atmosphere. Suspended solids, organic and inorganic particles, dissolved solids, heavy metals, dyes, and other impurities contained in wastewater from various sources are toxic to the atmosphere and pose serious health risks to humans and animals. Coagulation-flocculation technology is commonly used in wastewater treatment to remove cell debris, colloids, and contaminants in a comfortable and effective manner. Flocculants, both organic and inorganic, have long been used in wastewater treatment. However, because of their low performance, non-biodegradability, and associated health risks, their use has been limited. The use of eco-friendly bioflocculants in wastewater treatment has become essential due to the health implications of chemical flocculants. Because of their availability, biodegradability, and protection, plant-derived coagulants/flocculants and plant-based grafted bioflocculants have recently made significant progress in wastewater treatment. This study will undoubtedly provide a clearer understanding of the current state, challenges, and solutions for bioflocculation in wastewater remediation using green materials for the sake of a cleaner climate.Organochlorines have diverse structures and applications and are included in the list of persistent organic pollutants (POPs) due to their toxicity and environmental persistence. The reduced capacity of conventional wastewater treatment plants to remove these compounds encourages the development of cost-effective and efficient remediation approaches. Fungal biotechnology can contribute to the development of these technologies through their enzymatic machinery but faces several drawbacks related to the use of dispersed mycelium. In this sense, investigations concerning the degradation of organochlorines using immobilized fungi demonstrated an increase in contaminant removal efficiency compared with degradation by free cells. https://www.selleckchem.com/products/PP242.html Despite this interest, the mechanisms of immobilized fungi have not been comprehensively reviewed. In this paper, recent advances of laboratory and field studies in organochlorine compounds removal by fungi are reviewed, focusing on the role of immobilization techniques. Firstly, the mechanisms of organochlorines bioconversion by fungi and the factors affecting enzyme activity are elucidated and discussed in detail. Then, the main targeted compounds, fungi, technics, and materials used for immobilization are discussed, as well as their advantages and limitations. Furthermore, critical points for future studies of fungi immobilization for organochlorine removal are proposed.Problematic smartphone use (PSU) is growing rapidly among teens. It has similar presentations as other behavioral addictions in terms of excessive use, impulse control problems, and negative consequences. However, the underlying neurobiological mechanisms remain undiscovered. We hypothesized that structural changes in the striatum might serve as an important link between alteration in glutamate signaling and development of PSU.
Among 88 participants, twenty (FM, 128; age 16.2 ± 1.1) reported high scores in the smartphone addiction proneness scale (SAPS) with a cut-off score of 42; the other 68 (FM, 1949; age 15.3 ± 1.7) comprised the control group. Sociodemographic data and depression, anxiety, and impulsivity traits were measured. Striatal volumes (caudate, putamen, and nucleus accumbens) were estimated from T1 imaging data. Serum glutamate levels were estimated from peripheral blood samples. Group comparisons of each data were performed after controlling for age and gender. Mediation analyses were conducted to test the indirect effects of glutamate level alteration on PSU through striatal volumetric alteration.
The PSU group showed a decrease in both caudate volumes than the control group. Left caudate volume was positively correlated with serum glutamate level, and negatively with impulsivity traits and SAPS scores. The mediation model revealed a significant indirect effect of serum glutamate on SAS scores through the reduced left caudate volume.
This study suggests that altered glutamatergic neurotransmission may be associated with PSU among teens, possibly through reduced left caudate volume. Current findings might support neural mechanisms of smartphone addiction.
This study suggests that altered glutamatergic neurotransmission may be associated with PSU among teens, possibly through reduced left caudate volume. Current findings might support neural mechanisms of smartphone addiction.Social variables including parental and family factors may serve as risk factors for Internet Gaming Disorder (IGD) in adolescents. An IGD treatment programme should address these factors. We assessed two family therapies - multidimensional family therapy (MDFT) and family therapy as usual (FTAU) - on their impact on the prevalence of IGD and IGD symptoms.
Eligible for this randomised controlled trial comparing MDFT (N = 12) with FTAU (N = 30) were adolescents of 12-19 years old meeting at least 5 of the 9 DSM-5 IGD criteria and with at least one parent willing to participate in the study. The youths were recruited from the Centre Phénix-Mail, which offers outpatient adolescent addiction care in Geneva. Assessments occurred at baseline and 6 and 12 months.
Both family therapies decreased the prevalence of IGD across the one-year period. Both therapies also lowered the number of IGD criteria met, with MDFT outperforming FTAU. There was no effect on the amount of time spent on gaming. At baseline, parents judged their child's gaming problems to be important whereas the adolescents thought these problems were minimal. This discrepancy in judgment diminished across the study period as parents became milder in rating problem severity. MDFT better retained families in treatment than FTAU.
Family therapy, especially MDFT, was effective in treating adolescent IGD. Improvements in family relationships may contribute to the treatment success. Our findings are promising but need to be replicated in larger study.
ISRCTN 11142726.
ISRCTN 11142726.